Ron lives from day to day. Smoke like a dragon, he likes bourbon, women and rodeo. Nothing more than a quick and simple pleasures. The message that is HIV positive for him shocking sentence, which does not want to reconcile. The more that in its environment, this disease is associated exclusively with homosexuals, and he is not. Goes to Mexico, which intends to smuggle drugs banned in the U.S.. After returning unexpectedly gains an ally in the person of queer transsexual Rayon - "Leto is simply wonderful as the eccentric character in a Supporting Role" (The Hollywood Reporter). This seemingly discordant duet together begins to lead the club where others seek help. Ron is a man far from ideal, but with great strength of character. McConaughey "gave both roughness and the real charm of the character. Teetering on the straight lines masterfully. (...) It is poignant, but it is remarkable how much humor he managed to sneak into the story of a man being in the situation "(The Hollywood Reporter). The film is not a display of one actor - "hidden depth owes a supporting cast (...), gave a chance to Jennifer Garner on her best role since the Juno and breathed new life into his career Jared Leto" (The Telegraph).