Legandarny team - Michelangelo, Donatello, Raphael and Leonardo - are back on the big screen to again confront the wicked - even more evil, more cunning and ruthless. At their side once again become a beautiful April O'Neal (Megan Fox), Vern Fenwick (Will Arnett) and a new hero series - Casey Jones (Stephen Amell)
After that, when superzłoczyńcy Shredderowi again managed to escape justice, he joins forces with a mad scientist Baxter Stockman (Tyler Perry) and its two allies - Bebop (Gary Anthony Williams) and Rocksteadym (Stephen "Sheamus" Farrelly). Together, they try to put into practice a diabolical plan to take over the world. When the turtles are preparing to disrupt Shredder, it turns out that they have to confront the evil of which did not have a clue. Mysterious Krangowi, characters from another dimension ...